科研成就
近年生化系科研论文代表作
1. Bie J#, Li R#, Li Y, Song C, Chen Z, Zhang T, Tang Z, Su L, Zhu L, Wang J, Wan Y, Chen J*, Liu X*, Li T*, Luo J*(罗建沅). (2024) PKM2 aggregation drives metabolism reprograming during aging process. Nat Commun. 2024 Jul 9;15(1):5761.IF: 14.7
2. Chen K#, Li T#, Diao H, Wang Q, Zhou X, Huang Z, Wang M, Mao Z*(毛泽斌), Yang Y*, Yu W*(俞文华).SIRT7 knockdown promotes gemcitabine sensitivity of pancreatic cancer cell via upregulation of GLUT3 expression. Cancer Lett. 2024 Aug 28;598:217109. IF: 9.7
3. Bie J#, Li Y#, Song C, Weng Q, Zhao L, Su L, Zhao Z, Ye Y, Shen Z*, Ji J*, Luo J*(罗建沅). (2024) LAMTOR1 ablation impedes cGAS degradation caused by chemotherapy and promotes antitumor immunity. Proc Natl Acad Sci U S A. 2024 Oct 8;121(41):e2320591121. IF: 9.4
4. Minghe Fan, Sihan Huo, YuyaoGuo, Ruoxuan Wang, WenqinHao, Ziyang Zhang, Lina Wang, Ying Zhao*(赵颖). UDP-glucose dehydrogenase supports autophagy-deficient PDAC growth via increasing hyaluronic acid biosynthesis. Cell Rep. 2024 Feb 27;43(2):113808. doi: 10.1016/j.celrep.2024.113808. Epub 2024 Feb 16.IF: 7.5
5. Zhou Y#, Zhang T, Wang S, Jiao Z, Lu K, Liu X, Li H, Jiang W, Zhang X*(张晓伟). Metal-Polyphenol-Network coated R612F nanoparticles reduce drug resistance in hepatocellular carcinoma by inhibiting stress granules. Cell Death Discov. 2024, 10:384.IF: 6.1
6. Lin He, Chunyu Yu, Sen Qin, Enrun Zheng, Xinhua Liu, Yanhua Liu, Shimiao Yu, Yang Liu, Xuelin Dou, Zesen Shang, Yizhou Wang, Yue Wang, Xuehong Zhou, Boning Liu, YupingZhong, Zhiqiang Liu, Jin Lu, Luyang Sun*(孙露洋)(2023). The proteasome component PSMD14 drives myelomagenesis through a histone deubiquitinase activity. Molecular Cell 83: 1-17. IF: 16.0
7. Wenting Zhang, Yue Wang, Yongjie Liu, Cuifang Liu, Yizhou Wang, Lin He, Xiao Cheng, Yani Peng, Lu Xia, Xiaodi Wu, Jiajing Wu, Yu Zhang, Luyang Sun, Ping Chen, Guohong Li, Qiang Tu, Jing Liang*(梁静),Yongfeng Shang*(尚永丰). NFIB facilitates replication licensing by acting as a genome organizer. Nature Communications. 2023 Aug 21; 14(1):5076.IF: 16.6
8. Zhaoqi Shu, Minghe Fan, Bo Tu, Zhiheng Tang, Haojie Wang, Haimeng Li, Hengchao Li, Meng Yuan , Jingru Bai, Sihan Huo, Lina Wang, Wei-Guo Zhu, Wei Wang, Xiaoyun Liu, Shaokun Shu,Ying Zhao*(赵颖). The Lin28b/Wnt5a axis drives pancreas cancer through crosstalk between cancer associated fibroblasts and tumor epithelium. Nat Commun. 2023 Oct 28; 14(1):6885. doi: 10.1038/s41467-023 -42508-8 IF:16.6
9. Yuan M, Tu B, Li H, Pang H, Zhang N, Fan M, Bai J, Wang W, Shu Z, DuFort CC, Huo S, Zhai J, Yao K, Wang L, Ying H, Zhu WG, Fu D, Hu Z, Zhao Y*(赵颖). Nat Cancer. 2022 Aug;3(8):945-960. doi: 10.1038/s43018-022-00426-6. Epub 2022 Aug 18.(article,第1完成单位, IF 23.177)
10. Wang Y, Huang Y, Cheng E, Liu X, Zhang Y, Yang J, Young J, Brown G, Yang X*, Shang Y*(尚永丰). LSD1 is required for euchromatic origin firing and replication timing. Signal Transduction and Targeted Therapy. 2022 Apr 13; 7(1):102.(article,第1完成单位, IF 38.12)
11.Cheng X, Gu X, Xia T, Ma Z, Yang Z, Feng H, Zhao Y, Ma W, Ju Z, Gorospe M, Yi X, Tang H*, Wang W*(王文恭). HuB and HuD repress telomerase activity by dissociating HuR from TERC. Nucleic Acids Res. 2021 Mar 18; 49(5):2848-2858.(article,第1完成单位, IF 19.328)
12.Liu X, Xu B, Yang J, He L, Zhang Z, Cheng X, Yu H, Liu X, Jin T, Peng Y, Huang Y, Xia L, Wang Y, Wu J, Wu X, Liu S, Shan L, Yang X, Sun L, Liang J, Zhang Y*(张宇) and Shang Y*(尚永丰)(2021). UHRF2 commissions the completion of DNA demethylation through allosteric activation by 5hmC and K33-linked ubiquitination of XRCC1. Molecular Cell. 81: 1-15(article,第1完成单位, IF 19.328)
13. Liu X, Si W, He L, Yang J, Peng Y, Ren J, Liu X, Jin T, Yu H, Zhang Z, Cheng X, Zhang W, Xia L, Huang Y, Wang Y, Liu S, Shan L, Zhang Y, Yang X, Li H, Liang J, Sun L*(孙露洋) and Shang Y* (尚永丰)(2021). The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuitry. Signal Transduction and Targeted Therapy. 6:375(article,第1完成单位, IF 38.12)
14.Yu H#, Bu C#, Liu Y, Gong T, Liu X, Liu S, Peng X, Zhang W, Peng Y, Yang J, He L, Zhang Y, Yi X, Yang X, Sun L, Shang Y, Cheng Z*, Liang J*. Global crotonylome reveals CDYL-regulated RPA1 crotonylation in homologous recombination–mediated DNA repair, Science Advances, 2020 13;6(11):eaay4697.
15. Wang Z, Yang X, Liu C, Li X, Zhang B, Wang B, Zhang Y, Song C, Zhang T, Liu M, Liu B, Ren M, Jiang H, Zou J, Liu X, Zhang H, Zhu W, Yin Y, Zhang Z, Gu W, and Luo J(罗建沅). (2019) Acetylation of PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing mediated upregulation of KDM3A. Mol. Cell 74:1250-1263.
16. Ting X, Xia L, Yang J, He L, Si W, Shang Y, and Sun L(孙露洋)* (2019). USP11 Acts as a Histone Deubiquitinase Functioning in Chromatin Reorganization during DNA Repair. Nucleic Acids Research 47(18):9721-9740(article,第1完成单位, IF 19.328)
17. Yuan F(原逢杰,导师赵颖教授), Jin X, Li D, Song Y, Zhang N, Yang X, Wang L, Zhu WG, Tian C, Zhao Y*(赵颖教授). ULK1 phosphorylates Mad1 to regulate spindle assembly checkpoint. Nucleic Acids Res. 2019 Sep 5;47(15):8096-8110.(article,第1完成单位, IF 19.328)